Monoclonal Antibodies MCQs

Question 1

It is highly valued if the lymphocytes derived from the lymph node or tonsil tend to undergo fusion at

Accepted Answer

high frequencies

Answer

moderate frequencies

Answer

low frequencies

Answer

at no frequency

Question 2

Small simple molecules are

Accepted Answer

poor antigens

Answer

rich antigens

Answer

moderate antigens

Answer

heterophilic antigens

Question 3

The EBV-hybridoma technique

Accepted Answer

all of the above

Answer

immortalizes the donor Bcells

Answer

facilitates the proliferation of antigen specific B cells

Answer

gives much higher hybridization frequencies

Question 4

Helper T cells assist in the functions of

Accepted Answer

certain B cells and other T cells

Answer

certain B cells

Answer

certain T cells

Answer

none of the above

Question 5

In immuno-inflammatory diseases such as hemolytic anaemia, eczema etc.,

Accepted Answer

T8 cells are greatly reduced

Answer

T8 cells are greatly increased

Answer

T4 cells are greatly reduced

Answer

T4 cells are greatly increased

Question 6

Which of the following is incorrect?

Accepted Answer

MAbs can not be used in such non-infectious diseases as those of endocrine system

Answer

MAbs can be used to diagnose or treat diseases

Answer

MAbs can be used in tumor scanning

Answer

MAbs canbe used in cancer diagnosis

Question 7

The antigen-specific lymphocytes can be immortalized by which of the following method?

Accepted Answer

All of the above

Answer

Transfection with tumor derived DNA

Answer

Hybridization with a suitable lymphoid tumor cell

Answer

Transformation following infection by Epstein-Barr virus (EB V)

Question 8

A cytokine that stimulates the activity of B and T cells is

Accepted Answer

interlukin-2

Answer

lymphotoxin

Answer

interlukin-1

Answer

all of these

Question 9

Which type of cell actually secrets antibodies?

Accepted Answer

plasma cells

Answer

T cells

Answer

macrophages

Answer

dendritic cells