Molecular Biology and Genetics MCQs

Match the classes of RNA molecules in Group I with their functions in Group II. Group I Group II P. snoRNA 1. Protects germline from transposable elements Q. piRNA 2. Blocks translation of selected mRNA R. miRNA 3. Template for telomere elongation S. snRNA 4. Modification and processing of rRNA 5. Splicing of RNA transcripts

Reverse genetics means

The cellular process which utilizes RNA-induced silencing complex to block gene expression is

Match the type of chromosomal inheritance (Column I) with the corresponding genetic disease or trait (Column II). Column I Column II P. Autosomal recessive inheritance 1. Huntington disease Q. Autosomal dominant inheritance 2. Hairy ears R. X-linked inheritance 3. Cystic fibrosis S. Y-linked inheritance 4. Hemophilia

Protein P becomes functional upon phosphorylation of a serine residue, replacing this serine with . . . . . . . . will result in a phosphomimic mutant of P.

The RNA primer synthesized during the replication process in bacteria is removed by

A disease is inherited by a child with a probability of $${1 \over 4}$$. In a family with two children, the probability that exactly one sibling is affected by this disease is

The term 'protein splicing' refers to

Match the terms in Group I with the ploidy in Group II. Group I Group II P. Disome 1. 2n + 1 Q. Monosome 2. 2n - 1 R. Nullisome 3. n - 1 S. Trisome 4. n + 1