Computational Tools in Biotechnology MCQs

An example of a derived protein structure database is

The suitable substitution matrix to align closely related sequences is

Identify the character-based method(s) used for the construction of a phylogenetic tree. P. Maximum parsimony Q. Neighbor joining R. Maximum likelihood S. Bootstrapping

An example of a program for constructing a phylogenetic tree

Amino acid sequences of cytochrome c and ribulose 5-phosphate epimerase from 40 organisms were chosen and phylogenetic trees were obtained for each of these two protein families. Determine the correctness or otherwise of the following Assertion [A] and the Reason [R]. Assertion [A]: The two trees will not be identical. Reason [R]: The nature and frequency of mutations in the two families are different.

Match the items in Group I with an appropriate description in Group II. Group I Group II P. UPGMA 1. Protein sequence database Q. CLUSTAL 2. Phylogenetic analysis R. SWISS-PROT 3. 3-D structure visualization S. RasMol 4. Multiple sequence alignment

Number of unrooted trees in a phylogeny of five sequences is

Which one of these is a nucleotide sequence data base?

The term "Flybase" is a . . .