Bioinformatics and Biosensors MCQs

Question 1

Bioreporters refer to

Accepted Answer

Intact, living microbial cells-genetically engineered

Answer

Reporters working on biology

Answer

Reporters who know biology

Answer

None of the above

Question 2

Which type of genomics studies the physical nature of genomes?

Accepted Answer

Structural genomics

Answer

Comparative genomics

Answer

Functional genomics

Answer

None of these

Question 3

Which among the following is a compiled programming language?

Accepted Answer

PERL

Answer

FORTRAN

Answer

Bash script

Answer

AWK

Question 4

Luciferases can be found in bacteria, algae, fungi, jellyfish, insects, shrimp and squid and the resulting light that these organisms produce is termed

Accepted Answer

Bioluminescence

Answer

Luminescence

Answer

Fluorescence

Answer

Electrophoresis

Question 5

Match the following and select the correct answer: Column-I Column-II a. UPGMA 1. Protein sequence database b. CLUSTAL 2. Phylogenetic analysi c. SWISS-PROT 3. 3-D structure visualization d. Ras Mol 4. Multiple sequence alignment

Accepted Answer

a-2, b-4, c-1, d-3

Answer

a-1, b-4, c-2, d-3

Answer

a-4, b-1, c-2, d-3

Answer

a-3, b-2, c-4, d-1

Question 6

The genome-wide comparative mRNA expression profile between normal and cancer cells can be studied using the microarray technology. The basic approach of this technology is

Accepted Answer

Hybridization of fluorescently labelled cDNAs from normal and cancer cells to a single glass slide containing immobilized clones of human cDNAs

Answer

Hybridization of fluorescently labelled genomic DNA from human cells to normal and cancer cell cDNA immobilized onto two glass slides

Answer

Hybridization of fluorescently labelled cDNAs from normaland cancer cells to a single glass slide containing immobilized clones of human genomic DNA

Answer

Hybridization of fluorescently labelled genomic DNA from normal and cancer cells to immobilized human cDNAs on a single glass slide

Question 7

Sequence analysis of a human gene NFI showed that a region of the protein has homology to a yeast protein called Ira. Which of the following you think is most appropriate explanation for this sequence homology?

Accepted Answer

Human and yeast are closely related

Answer

The homology is of no significance

Answer

The similarity might reflect a common function

Answer

More information is required for making any conclusion

Question 8

Which of the following is the most preferred website for searching original research articles in medicine?

Accepted Answer

Entrez

Answer

Coogle

Answer

MSN

Answer

EMBL

Question 9

Which bacterial genome was the first to be completely sequenced?

Accepted Answer

Haemophilus influenzae

Answer

E. coli

Answer

Streptococcus pneumoniae

Answer

None of the above